Well unfortunatly

our Ford shop truck got stolen and I have to buy a new truck.
Im going back to Dodge now that they have the new auto tranny.
Im looking at a 08' 3500 4WD dually. I want to run 22.5 wheels and tires. I am going to put a flatbed on it.
Dealer has one on the lot (with 22.5's) cloth interior, and we are negotiating around 41K.
Daily driver, Tow 5th wheel and trailers up to 12K.
Questions:
Any issues out there with wheel adapters and the big tires, any recomendations?
Truck has 3.73 gears, should I look for 4.10's?
Any other thoughts, I have been out of the dodge seen for a few years.